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CARD11 (M12) polyclonal antibody（KU）

货号: BS2228

价格：￥ 1140

货期：现货（1-2个工作日）

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详细信息检测数据实验指南文献

No. :BS2228

Product Name :CARD11 (M12) polyclonal antibody（KU）

Swiss-Prot :Q9BXL7

Host :Rabbit

Reactivity :Human,Rat

Applications :WB

Application_all :WB: 1:500~1:1000

Background :The protein encoded by this gene belongs to the membrane-associated guanylate kinase (MAGUK) family, a class of proteins that functions as molecular scaffolds for the assembly of multiprotein complexes at specialized regions of the plasma membrane. This protein is also a member of the CARD protein family, which is defined by carrying a characteristic caspase-associated recruitment domain (CARD). This protein has a domain structure similar to that of CARD14 protein. The CARD domains of both proteins have been shown to specifically interact with BCL10, a protein known to function as a positive regulator of cell apoptosis and NF-kappaB activation. When expressed in cells, this protein activated NF-kappaB and induced the phosphorylation of BCL10.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :CARD11 polyclonal antibody detects endogenous levels of CARD11 protein.

BiowMW :~ 133 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Caspase recruitment domain-containing protein 11; CARD-containing MAGUK protein 1; Carma 1; CARD11; CARMA1

Immunogen :Recombinant full length Human CARD11.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of Carma 1 (M12) pAb at 1:500 dilution Lane1:K562 whole cell lysate(40ug) Lane2:The Thymus tissue lysate of Rat(30ug) Lane3:Myla2059 whole cell lysate(40ug)