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BRD3 (F645) polyclonal antibody

货号: BS2064

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS2064

Product Name :BRD3 (F645) polyclonal antibody

Swiss-Prot :Q15059

Host :Rabbit

Reactivity :Human

Applications :WB IHC

Application_all :WB:1:500~1:1000 IHC: 1:50~1:200

Background :The bromodomain-containing proteins include BRD2, BRD3, BRD4 and BRDT. BRD2 (RING3 protein) is a mitogen-activated nuclear protein whose gene is located in the human MHC II region, suggesting its relation to HLA-associated diseases. The gene encoding BRD3 (RING3-like protein) contains two bromodomains and maps to chromosome 9q34. BRD4 (HUNK1 protein) is a nuclear protein involved in the regulation of chromosomal dynamics during mitosis. The testis-specific bromodomain protein BRDT contains a PEST sequence, indicating that it undergoes rapid intracellular degradation. The bromodomaincontaining proteins are ubiquitously expressed.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :BRD3 (F645) polyclonal antibody detects endogenous levels of BRD3 protein.

BiowMW :~72 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Bromodomain-containing protein 3; RING3-like protein; BRD3; KIAA0043; RING3L

Immunogen :Synthetic peptide, corresponding to amino acids 614-667 of Human BRD3.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of BRD3 pAb at 1:1000 dilution Lane1:SGC7901 whole cell lysate(40ug) Lane2:HEK293T whole cell lysate(40ug) Lane3:Jurkat whole cell lysate(40ug)

Immunohistochemistry (IHC) analyzes of BRD3 (F645) pAb in paraffin-embedded human breast carcinoma tissue at 1:50.