产品类别

联系我们

电话:025-68037686

地址:江苏生命科技创新园F6幢1层

订购:nanjing03@biogot.com

服务:biorase01@biogot.com

合作:lvyun@biogot.com

支持:may@biogot.com

AKAP 95 (E363) polyclonal antibody（KU）

货号: BS1878

价格：￥ 1140

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

抗体定制服务咨询

说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS1878

Product Name :AKAP 95 (E363) polyclonal antibody（KU）

Swiss-Prot :O43823

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB

Application_all :WB: 1:500~1:1000

Background :The type II cAMP-protein kinase (PKA) is a multifunctional kinase with a broad range of substrates. Specificity of PKA signaling is thought to be mediated by the compartmentalization of the kinase to specific sites within the cell. To maintain this specific localization, the R subunit (RII) of PKA interacts with specific RII-anchoring proteins. The family of RII-anchoring proteins has been designated A-kinase anchoring proteins (AKAP). AKAP 95, also known as AKAP 8, is a nuclear matrix protein predominantly expressed in liver, heart, pancreas, kidney and skeletal muscle. During mitosis, AKAP 95 is recruited to the chromosomes and plays an essential role in mitotic progression. Characteristic of its family, AKAP 95 participates in PKA signaling through an interaction with the RII regulatory subunit. In addition, AKAP 95 forms a complex with HA95 and HDAC3 and is required for the deacetylation of Histone H3 in mitosis.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :AKAP 95 (E363) pAb detects endogenous levels of AKAP 95 (E363) protein.

BiowMW :~ 76 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial; Complex I-KFYI; CI-KFYI; NADH-ubiquinone oxidoreductase KFYI subunit; NDUFC1

Immunogen :Synthetic peptide, corresponding Human NDUFC1.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of AKAP 95 (E363) pAb at 1:500 dilution Lane1:EC9706 whole cell lysate(40ug) Lane2:HepG2 whole cell lysate(40ug) Lane3:HEK293T whole cell lysate(40ug) Lane4:AML-12 whole cell lysate(40ug) Lane5:H9C2 whole cell lysate(40ug)