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Caspase 9 (R192) polyclonal antibody

货号: BS1731

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS1731

Product Name :Caspase 9 (R192) polyclonal antibody

Swiss-Prot :P55211

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB IHC IF

Application_all :WB: 1:500~1:1000 IHC: 1:50~1:200 IF: 1:50~1:200

Background :Caspase 9 (also known as ICE like apoptotic protease 6 (ICE LAP6), apoptotic protease Mch6, and apoptotic protease activating factor 3 (Apaf3)) is a member of the peptidase family C14 that contains a CARD domain. This caspase is active as a heterotetramer and has been reported to have two isoforms. ProCaspase 9 has been reported to be approximately 47 kD. This caspase is present in the cytosol and, upon activation, translocates to the mitochondria. Caspase 9 is involved in the caspase activation cascade responsible for apoptosis execution and cleaves/activates Caspase 3 and Caspase 6.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Caspase 9 (R192) polyclonal antibody detects endogenous levels of Caspase 9 protein.

BiowMW :~ 35,48 kDa

Note :For research use only, not for use in diagnostic procedure.

Pathway :Regulation of Apoptosis,Inhibition of Apoptosis,Mitochondrial Control of Apoptosis,Death Receptor Signaling,

Alternative Name :CASP 9; Caspase9; Caspase-9; CASP-9; Apoptotic protease Mch-6; Apoptotic protease-activating factor 3; APAF-3; ICE-like apoptotic protease 6; ICE-LAP6; Caspase-9 subunit p35; Caspase-9 subunit p10; CASP9; MCH6

Immunogen :Synthetic peptide, corresponding to amino acids 280-320 of Human Caspase 9.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of Caspase 9 (R192) polyclonal antibody at 1:500 dilution Lane1:Hela cell lysate Lane2:sp2/0 cell lysate Lane3:H9C2 cell lysate

Immunohistochemistry (IHC) analyzes of Caspase 9 (R192) pAb in paraffin-embedded human breast carcinoma tissue at 1:100.

AIM2 promotes non‐small‐cell lung cancer cell growth through inflammasome‐dependent pathway

JournalJournal Of Cellular Physiology

ApplicationWB

IF4.522

SpeciesHuman

PMID30953357
Phosphoribosyl-pyrophosphate synthetase 2 (PRPS2) depletion regulates spermatogenic cell apoptosis and is correlated with hypospermatogenesis

JournalAsian Journal Of Andrology

ApplicationIHC,WB

IF2.448

SpeciesMouse

PMID31736475
Prodigiosin from Serratia Marcescens in Cockroach Inhibits the Proliferation of Hepatocellular Carcinoma Cells through Endoplasmic Reticulum Stress-Induced Apoptosis

JournalMOLECULES

ApplicationWB

IF4.927

SpeciesHuman

PMID36364107