产品类别

联系我们

电话:025-68037686

地址:江苏生命科技创新园F6幢1层

订购:nanjing03@biogot.com

服务:biorase01@biogot.com

合作:lvyun@biogot.com

支持:may@biogot.com

ATP6 polyclonal antibody

货号: BS1681

价格：￥ 1140

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

抗体定制服务咨询

说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS1681

Product Name :ATP6 polyclonal antibody

Swiss-Prot :P00848

Host :Rabbit

Reactivity :Mouse,Rat

Applications :WB

Application_all :WB: 1:500~1:1000 IHC: 1:50~1:200

Background :ATP6, also known as MT-ATP6, ATPASE6 or MTATP6, is a 226 amino acidmulti-passmembrane protein that localizestomitochondria and functions as a component of the F0 proton channel, playing a direct role in the transport of protons acrossthe mitochondrial membrane. Defectsin the gene encoding ATP6 are the cause of infantile bilateralstriatal necrosis, Leigh syndrome (LS),Leber hereditary optic neuropathy(LHON) and neurogenic muscle weakness, ataxia, and retinitis pigmentosa (NARP), all of which are neurological or retinal disorders. The gene encoding ATP6 exists as part of themitochondrial genome.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :ATP6 polyclonal antibody detects endogenous levels of ATP6 protein.

BiowMW :~ 25 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :ATP synthase subunit a; F-ATPase protein 6; Mtatp6; Atp6; Atpase6; mt-Atp6

Immunogen :A synthetic peptide corresponding to amino acids 55-70 of Mouse ATP6.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of ATP6 polyclonal antibody at 1:1000 dilution Lane1:The muscle tissue lysate of Rat (47μg) Lane2:The muscle tissue lysate of Mouse(37μg)

The Involvement of Protease Nexin-1 (PN1) in the Pathogenesis of Intervertebral Disc (IVD) Degeneration

JournalScientific Reports

ApplicationWB

IF4.011

SpeciesHuman

PMID27460424
TGF‐β Stimulates Expression of Chondroitin Polymerizing Factor in Nucleus Pulposus Cells Through the Smad3, RhoA/ROCK1, and MAPK Signaling Pathways

JournalJournal Of Cellular Biochemistry

ApplicationWB

IF3.448

SpeciesRat

PMID28608941
Transcriptional Study Revealed That Boron Supplementation May Alter the Immune-Related Genes Through MAPK Signaling in Ostrich Chick Thymus

JournalBiological Trace Element Research

ApplicationWB

IF2.639

SpeciesChicken

PMID30094741
The chimeric gene atp6c confers cytoplasmic male sterility in maize by impairing the assembly of mitochondrial ATP synthase complex

JournalMolecular Plant

ApplicationWB

IF13.164

SpeciesPlant（Rice）

PMID35272047