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Cbl (E768) polyclonal antibody（KU）

货号: BS1439

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS1439

Product Name :Cbl (E768) polyclonal antibody（KU）

Swiss-Prot :P22681

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB IHC IF

Application_all :WB: 1:500~1:1000 IHC: 1:50~1:200 IF: 1:50~1:200

Background :Cbl (also designated the c-Cbl proto-oncogene, E3 ubiquitin-protein ligase CBL, Casitas B-lineage lymphoma proto-oncogene and RING finger protein 55) has been identified as the cellular homolog of the v-Cbl oncogene isolated from an NFS/N mouse that developed a pre-B cell lymphoma following infection with the replication-competent Cas Br-M murine leukemic virus. c-Cbl is expressed at relatively high levels in a wide range of hematopoietic tumor cell lines as well as in normal tissues such as thymus and testis.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :CBL (E768) polyclonal antibody detects endogenous levels of CBL protein.

BiowMW :~ 100, 120kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :E3 ubiquitin-protein ligase CBL; Casitas B-lineage lymphoma proto-oncogene; Proto-oncogene c-Cbl; RING finger protein 55; Signal transduction protein CBL; CBL; CBL2; RNF55

Immunogen :Synthetic peptide, corresponding to amino acids 740-790 of Human Cbl.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of Cbl (E768) pAb at 1:500 dilution Lane1:PC12 whole cell lysate(40ug) Lane2:BV2 whole cell lysate(40ug) Lane3:HCT116 whole cell lysate(40ug) Lane4:MCF-7 whole cell lysate(40ug)

Immunohistochemistry (IHC) analyzes of Cbl (E768) pAb in paraffin-embedded human breast carcinoma tissue at 1:100.