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COX-2 (T594) polyclonal antibody（KU）

货号: BS1076

价格：￥ 1140

货期：现货（1-2个工作日）

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详细信息检测数据实验指南文献

No. :BS1076

Product Name :COX-2 (T594) polyclonal antibody（KU）

Swiss-Prot :P35354

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB IHC IF

Application_all :WB: 1:500~1:1000 IHC: 1:50~1:200 IF: 1:50~1:200

Background :Prostaglandins are a diverse group of autocrine and paracrine hormones that mediate many cellular and physiologic processes. Prostaglandin H2 (PGH2) is an intermediate in formation of the prostaglandins. Two prostaglandin synthases that catalyze the formation of PGH2 from arachidonic acid (AA) are cyclooxygenase-1 and cyclooxygenase-2. Cyclooxygenase-2, or Cox-2, is efficiently induced in migratory cells responding to pro-inflammatory stimuli and is considered to be an important mediator of inflammation. An alternative form of the protein, designated Cox-1, is constitutively expressed in most tissues and is thought to serve in general “housekeeping” functions. Both enzymes are targets for the nonsteroidal therapeutic anti-inflammatorydrugs, NSAIDs.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Cox2 (T594) polyclonal antibody detects endogenous levels of Cox2 protein.

BiowMW :~ 74 kDa

Note :For research use only, not for use in diagnostic procedure.

Pathway :Immune Cell Signaling,

Alternative Name :Prostaglandin G/H synthase 2; Cyclooxygenase-2; COX-2; PHS II; Prostaglandin H2 synthase 2; PGH synthase 2; PGHS-2; PGHS2; Prostaglandin-endoperoxide synthase 2; PTGS2; COX2

Immunogen :Synthetic peptide, corresponding to amino acids C-terminus of Human Cox-2.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of Cox-2 (T594) polyclonal antibody at 1:500 dilution Lane1:CT26 whole cell lysate(20ug) Lane2:PC12 whole cell lysate(40ug) Lane3:Hela whole cell lysate(40ug)

Immunohistochemistry (IHC) analyzes of Cox-2 (T594) pAb in paraffin-embedded human breast carcinoma tissue at 1:100.

Neuroprotective Effects of Eugenol Acetate Against Ischemic Stroke

JournalJournal of Inflammation Research

ApplicationWB

IF4.2

SpeciesMouse

PMID39802508
Methanol Extract of Pueraria lobata (Willd.) Root and Its Active Ingredient, Puerarin, Induce Apoptosis in HeLa Cells and Attenuates Bacterial Vaginosis in Gardnerella vaginalis-Infected Mice

JournalINTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

ApplicationWB

IF4.9

SpeciesMouse

PMID39941110
Protective effect of Dendrobium officinale extract on aspirin-induced gastric lesions in rats

JournalMOLECULAR IMMUNOLOGY

ApplicationIHC,WB

IF3.2

SpeciesRat

PMID39919349