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PGC1α polyclonal antibody

货号: AP0774

价格：￥ 1140

货期：现货（1-2个工作日）

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详细信息检测数据实验指南文献

No. :AP0774

Product Name :PGC1α polyclonal antibody

Swiss-Prot :Q9UBK2

Host :Rabbit

Reactivity :Human, Mouse, Rat

Applications :WB, IHC, IF/ICC

Application_all :WB,1:500 - 1:1000|IHC,1:50 - 1:100|IF/ICC,1:50 - 1:100

Background :The protein encoded by this gene is a transcriptional coactivator that regulates the genes involved in energy metabolism. This protein interacts with PPARgamma, which permits the interaction of this protein with multiple transcription factors. This protein can interact with, and regulate the activities of, cAMP response element binding protein (CREB) and nuclear respiratory factors (NRFs). It provides a direct link between external physiological stimuli and the regulation of mitochondrial biogenesis, and is a major factor that regulates muscle fiber type determination. This protein may be also involved in controlling blood pressure, regulating cellular cholesterol homoeostasis, and the development of obesity.

Product :1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :PGC1α polyclonal antibody detects endogenous levels of PGC1α protein.

BiowMW :91KDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :LEM6; PGC1; PGC1A; PPARGC1; Peroxisome proliferator-activated receptor gamma coactivator 1-alpha; PGC-1-alpha; PPAR-gamma coactivator 1-alpha; PPARGC-1-alpha; Ligand effect modulator 6

Immunogen :KLH-conjugated synthetic peptide of human PGC1α.

Conjugate :Unconjugated

Modification :Unmodified

Western blot analysis of PGC1α expression in mouse heart (A), rat heart (B) whole cell lysates.

Immunohistochemical analysis of PGC1α staining in mouse kidney formalin fixed paraffin embedded tissue section.

Immunofluorescent analysis of PGC1α staining in HeLa cells.

Ginseng polysaccharide attenuates red blood cells oxidative stress injury by regulating red blood cells glycolysis and liver gluconeogenesis

JournalJOURNAL OF ETHNOPHARMACOLOGY

ApplicationWB

IF5.195

SpeciesRat

PMID36122792