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AURKB/C (K197) polyclonal antibody（KU）

货号: AP0464

价格：￥ 1140

货期：现货（1-2个工作日）

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详细信息检测数据实验指南文献

No. :AP0464

Product Name :AURKB/C (K197) polyclonal antibody（KU）

Swiss-Prot :Q96GD4/Q9UQB9

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB

Application_all :WB:1:500~1:1000

Background :Aurora kinases belong to a highly conserved family of mitotic serine/threonine kinases with three members identified among mammals: Aurora A, B, and C. Studies on the temporal expression pattern and subcellular localization of Aurora kinases in mitotic cells suggest an association with mitotic structure. Aurora kinase functional influences span from G2 phase to cytokinesis and may be involved in key cell cycle events such as centrosome duplication, chromosome bi-orientation and segregation, cleavage furrow positioning, and ingression.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 108% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :AURKB/C (K197) polyclonal antibody detects endogenous levels of AURKB and AURKC protein.

BiowMW :~ 55, 40, 45 kDa

Note :For research use only, not for use in diagnostic procedure.

Pathway :Regulation of Microtubule Dynamics,

Alternative Name :Aurora kinase B; Aurora 1; Aurora- and IPL1-like midbody-associated protein 1; AIM-1; Aurora/IPL1-related kinase 2; ARK-2; Aurora-related kinase 2; STK-1; Serine/threonine-protein kinase 12; Serine/threonine-protein kinase 5;Serine/threonine-protein kinase aurora-B; AURKB; AIK2; AIM1; AIRK2; ARK2; STK1; STK12; STK5; Aurora kinase C; Aurora 3; Aurora/IPL1-related kinase 3; ARK-3; Aurora-related kinase 3; Aurora/IPL1/Eg2 protein 2; Serine/threonine-protein kinase 13; Serine/threonine-protein kinase aurora-C; AURKC; AIE2; AIK3; AIRK3; ARK3; STK13

Immunogen :Synthetic peptide, corresponding to amino acids 163-213 of Human AURKB.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of AURKB/C (K197) pAb at 1:500 dilution Lane1:H1792 whole cell lysate(40ug) Lane2:HCT116 whole cell lysate(40ug) Lane3:LOVO whole cell lysate(40ug) Lane4:AML-12 whole cell lysate(40ug) Lane5:PMVEC whole cell lysate(40ug)