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Caspase 9 (E119) polyclonal antibody

货号: AP0359

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :AP0359

Product Name :Caspase 9 (E119) polyclonal antibody

Swiss-Prot :P55211

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB IHC IF

Application_all :WB: 1:500~1:1000 IHC: 1:50~1:200 IF: 1:50~1:200

Background :Caspase 9 (also known as ICE like apoptotic protease 6 (ICE LAP6), apoptotic protease Mch6, and apoptotic protease activating factor 3 (Apaf3)) is a member of the peptidase family C14 that contains a CARD domain. This caspase is active as a heterotetramer and has been reported to have two isoforms. ProCaspase 9 has been reported to be approximately 47 kD. This caspase is present in the cytosol and, upon activation, translocates to the mitochondria. Caspase 9 is involved in the caspase activation cascade responsible for apoptosis execution and cleaves/activates Caspase 3 and Caspase 6.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Caspase 9 (E119) polyclonal antibody detects endogenous levels of full length caspase-9 (48 kDa) and large fragments of caspase-9 (35 kDa/37 kDa).

BiowMW :~ 35, 37, 48 kDa

Note :For research use only, not for use in diagnostic procedure.

Pathway :Regulation of Apoptosis,Inhibition of Apoptosis,Mitochondrial Control of Apoptosis,Death Receptor Signaling,

Alternative Name :CASP 9; Caspase9; Caspase-9; CASP-9; Apoptotic protease Mch-6; Apoptotic protease-activating factor 3; APAF-3; ICE-like apoptotic protease 6; ICE-LAP6; Caspase-9 subunit p35; Caspase-9 subunit p10; CASP9; MCH6

Immunogen :Synthetic peptide, corresponding to amino acids 100-150 of Human Caspase 9.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of Caspase 9 (E119) polyclonal antibody at 1:500 dilution Lane1:CT26 whole cell lysate Lane2:L02 treated with PBS(1×PBS,PH7.4) for 240min whole cell lysate Lane3:L02 treated with PBS(1×PBS,PH7.4) for 120min whole cell lysate Lane4:L02 treated with PBS(1×PBS,PH7.4) for 60min whole cell lysate Lane5:L02 whole cell lysate

MicroRNA-26a-3p rescues depression-like behaviors in male rats via preventing hippocampal neuronal anomalies

JournalJournal Of Clinical Investigation

ApplicationWB

IF14.808

SpeciesRat

PMID34228643
miR-4293 upregulates lncRNA WFDC21P by suppressing mRNA-decapping enzyme 2 to promote lung carcinoma proliferation

JournalCell Death & Disease

ApplicationWB

IF8.469

SpeciesHuman

PMID34301920