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CD321 polyclonal antibody（KU）

货号: NCP0316P

价格：￥ 1140

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

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说明书 MSDS SHIP

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No. :NCP0316P

Product Name :CD321 polyclonal antibody（KU）

Swiss-Prot :Q9Y624

Host :Rabbit

Reactivity :Human

Applications :WB

Application_all :WB: 1:2000~1:5000

Background :Junctional Adhesion Molecule-A/F11 Receptor (JAM-A/F11R) is a transmembrane glycoprotein belonging to the immunoglobulin superfamily. JAM-A regulates multiple cellular processes, including tight junction assembly, epithelial-mesenchymal transition (EMT), leukocyte migration, virus binding, platelet activation, and angiogenesis. Aberrant expression of JAM-A is correlated with poor patient prognosis in several human cancers. In a mouse model of atherosclerosis, an antagonistic peptide that inhibits JAM-A-expressing platelets from interacting with inflamed endothelial cells reduces atherosclerotic plaque formation.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :CD321 polyclonal antibody detects endogenous levels of CD321 protein.

BiowMW :~ 38 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Junctional adhesion molecule A; JAM-A; Junctional adhesion molecule 1; JAM-1; Platelet F11 receptor; Platelet adhesion molecule 1; PAM-1; CD_antigen: CD321; F11R; JAM1; JCAM; UNQ264/PRO301

Immunogen :Recombinant protein of human CD321.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of CD321 polyclonal antibody at 1:2000 dilution Lane1:HEK293T whole cell lysate(30ug) Lane2:A549 whole cell lysate(30ug) Lane3:HepG2 whole cell lysate(30ug)