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CD167a polyclonal antibody（KU）

货号: NCP0289P

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

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No. :NCP0289P

Product Name :CD167a polyclonal antibody（KU）

Swiss-Prot :Q08345

Host :Rabbit

Reactivity :Human,Rat,Mouse

Applications :WB IF

Application_all :WB: 1:1000~1:2000 IF 1:50~1:200

Background :Tyrosine kinase that functions as cell surface receptor for fibrillar collagen and regulates cell attachment to the extracellular matrix, remodeling of the extracellular matrix, cell migration, differentiation, survival and cell proliferation. Collagen binding triggers a signaling pathway that involves SRC and leads to the activation of MAP kinases. Regulates remodeling of the extracellular matrix by up-regulation of the matrix metalloproteinases MMP2, MMP7 and MMP9, and thereby facilitates cell migration and wound healing. Required for normal blastocyst implantation during pregnancy, for normal mammary gland differentiation and normal lactation. Required for normal ear morphology and normal hearing.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :CD167a polyclonal antibody detects endogenous levels of CD167a protein.

BiowMW :~ 95 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Epithelial discoidin domain-containing receptor 1; Epithelial discoidin domain receptor 1; CD167 antigen-like family member A; Cell adhesion kinase; Discoidin receptor tyrosine kinase; HGK2; Mammary carcinoma kinase 10; MCK-10; Protein-tyrosine kinase 3A; Protein-tyrosine kinase RTK-6; TRK E; Tyrosine kinase DDR; Tyrosine-protein kinase CAK; DDR1; CAK, EDDR1, NEP, NTRK4, PTK3A, RTK6, TRKE

Immunogen :Recombinant protein of human CD167a.

Conjugate :Unconjugated

Modification :Unmodified

Western blot (WB) analysis of CD167a polyclonal antibody at 1:1000 dilution Lane1:BV2 whole cell lysate(30ug) Lane2:PC12 whole cell lysate(30ug) Lane3:MCF-7 whole cell lysate(30ug) Lane4:A375 whole cell lysate(30ug) Lane5:HEK293T whole cell lysate(30ug)

Immunofluorescence analysis of MCF-7 cells using CD167a pAb at dilution of 1:200.