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CD154 polyclonal antibody（KU）

货号: NCP0273P

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :NCP0273P

Product Name :CD154 polyclonal antibody（KU）

Swiss-Prot :P29965

Host :Rabbit

Reactivity :Human

Applications :WB

Application_all :WB: 1:2000~1:5000

Background :CD40 ligand (CD40L), also known as CD154, TRAP, and gp39, is the ligand for the TNF receptor family member CD40. CD40L is expressed either as a soluble cytokine or as a homotrimeric transmembrane protein. CD40L primarily expressed on the surface of T-cells, but has also been reported in blood platelets, mast cells, basophils, NK cells, and B-cells. It plays an important role in stimulating B-cell cell proliferation and survival and promotes immunoglobulin class switching and secretion of IgE. Signals generated by CD40 vary depending on cell type and include activation of MAPK pathways as well as NF-κB. Mutations within the CD40L gene are associated with X-linked hyper-IgM syndrome characterized by high serum levels of IgM and decreased levels of other isotypes. The CD40L/CD40 pathway is an important area of interest in the study of cancer, vascular diseases, and inflammatory disorders.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :CD154 polyclonal antibody detects endogenous levels of CD154 protein.

BiowMW :~ 34 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :CD40 ligand; CD40-L; T-cell antigen Gp39; TNF-related activation protein; TRAP; Tumor necrosis factor ligand superfamily member 5; CD154; CD40 ligand, membrane form; CD40 ligand, soluble form; sCD40L; CD40LG; CD40L; TNFSF5; TRAP

Immunogen :Recombinant protein of human CD154.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of CD154 polyclonal antibody at 1:2000 dilution Lane1:MCF-7 cell membrane lysate(24ug) Lane2:L02 cell membrane lysate(24ug) Lane3:EC9706 cell membrane lysate(24ug)