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CD113/NECTIN3 polyclonal antibody

货号: NCP0249P

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

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No. :NCP0249P

Product Name :CD113/NECTIN3 polyclonal antibody

Swiss-Prot :Q9NQS3

Host :Rabbit

Reactivity :Human,Rat,Mouse

Applications :IF

Application_all :IF: 1:100~1:500

Background :Plays a role in cell-cell adhesion through heterophilic trans-interactions with nectin-like proteins or nectins, such as trans-interaction with NECTIN2 at Sertoli-spermatid junctions. Trans-interaction with PVR induces activation of CDC42 and RAC small G proteins through common signaling molecules such as SRC and RAP1. Also involved in the formation of cell-cell junctions, including adherens junctions and synapses. Induces endocytosis-mediated down-regulation of PVR from the cell surface, resulting in reduction of cell movement and proliferation. Plays a role in the morphology of the ciliary body.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :CD113/NECTIN3 polyclonal antibody detects endogenous levels of CD113/NECTIN3 protein.

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Nectin-3; CDw113; Nectin cell adhesion molecule 3; Poliovirus receptor-related protein 3; CD113; NECTIN3 ; PRR3; PVRL3

Immunogen :Recombinant protein of human CD113/NECTIN3.

Conjugate :Unconjugated

Modification :Unmodified

Immunofluorescence analysis of MCF-7 cells using CD113/NECTIN3 pAb at dilution of 1:200 (40x lens).