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Integrin α5 (CD49e) polyclonal antibody（KU）

货号: NCP0244P

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :NCP0244P

Product Name :Integrin α5 (CD49e) polyclonal antibody（KU）

Swiss-Prot :P08648

Host :Rabbit

Reactivity :Human,Mouse

Applications :WB IP

Application_all :WB: 1:2000~1:5000 IP: 1:50~1:200

Background :Integrins are α/β heterodimeric cell surface receptors that play a pivotal role in cell adhesion and migration, as well as in growth and survival. The integrin family contains at least 18 α and 8 β subunits that form 24 known integrins with distinct tissue distribution and overlapping ligand specificities. Integrins not only transmit signals to cells in response to the extracellular environment (outside-in signaling), but also sense intracellular cues to alter their interaction with the extracellular environment (inside-out signaling). Integrin α5/β1 is involved in multiple biological processes including embryonic development, angiogenesis and tumor metastasis. By interaction with its fibronectin ligand, α5/β1 transduces signals that regulate cell adhesion, migration, matrix assembly and cytoskeletal organization.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Integrin α5 polyclonal antibody detects endogenous levels of Integrin α5 protein.

BiowMW :~ 130 kDa

Note :For research use only, not for use in diagnostic procedure.

Pathway :G Protein-coupled Receptors Signaling to MAPK Erk，MAPK Erk in Growth and Differentiation Pathway，PI3K AKT signaling

Alternative Name :Integrin alpha-5; CD49 antigen-like family member E; Fibronectin receptor subunit alpha; Integrin alpha-F; VLA-5; CD49e; Integrin alpha-5 heavy chain; Integrin alpha-5 light chain; ITGA5; FNRA

Immunogen :Recombinant protein of human Integrin α5.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of Integrin α5 polyclonal antibody at 1:2000 dilution Lane1:A549 whole cell lysate(30ug) Lane2:L02 cell membrane lysate(24ug) Lane3:SGC7901 whole cell lysate(30ug) Lane4:BV2 whole cell lysate(30ug)