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CD79A polyclonal antibody（KU）

货号: NCP0227P

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :NCP0227P

Product Name :CD79A polyclonal antibody（KU）

Swiss-Prot :P11912

Host :Rabbit

Reactivity :Rat,Mouse,Human

Applications :WB IF

Application_all :WB: 1:2000~1:5000 IF 1:50~1:200

Background :Required in cooperation with CD79B for initiation of the signal transduction cascade activated by binding of antigen to the B-cell antigen receptor complex (BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. Also required for BCR surface expression and for efficient differentiation of pro- and pre-B-cells. Stimulates SYK autophosphorylation and activation. Binds to BLNK, bringing BLNK into proximity with SYK and allowing SYK to phosphorylate BLNK. Also interacts with and increases activity of some Src-family tyrosine kinases. Represses BCR signaling during development of immature B-cells.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :CD79A polyclonal antibody detects endogenous levels of CD79A protein.

BiowMW :~ 45 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :B-cell antigen receptor complex-associated protein alpha chain; Ig-alpha; MB-1 membrane glycoprotein; Membrane-bound immunoglobulin-associated protein; Surface IgM-associated protein; CD79a

Immunogen :Recombinant protein of human CD79A.

Conjugate :Unconjugated

Modification :Unmodified

Western blot (WB) analysis of CD79A polyclonal antibody at 1:2000 dilution Lane1:C6 whole cell lysate(30ug) Lane2:CT-26 whole cell lysate(30ug) Lane3:SGC7901 whole cell lysate(30ug) Lane4:EC9706 cell membrane lysate(30ug) Lane5:MCF-7 cell membrane lysate(30ug)

Immunofluorescence analysis of SGC7901 cells using CD79A pAb at dilution of 1:200.