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CD70 polyclonal antibody（KU）

货号: NCP0224P

价格：￥ 1140

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :NCP0224P

Product Name :CD70 polyclonal antibody（KU）

Swiss-Prot :P32970

Host :Rabbit

Reactivity :Human,Mouse

Applications :WB IF

Application_all :WB: 1:2000~1:5000 IF: 1:100~1:500

Background :CD70 is a type II transmembrane glycoprotein and a member of the tumor necrosis factor ligand superfamily (TNFSF), also known as CD27L and TNFSF7. It is normally expressed on medullary thymic epithelial cells. Its expression is induced on activated lymphoid cells (B cells, T cells, and NK cells) and dendritic cells. CD70 is a ligand for CD27, a co-stimulatory receptor that plays an important role in T cell activation and proliferation. CD70 overexpression has been reported in various tumors such as renal cell carcinoma, glioblastoma, and non-small cell lung carcinoma and it’s being actively pursued as a therapeutic target.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :CD70 polyclonal antibody detects endogenous levels of CD70 protein.

BiowMW :~ 33 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :CD70 antigen; CD27 ligand; CD27-L; Tumor necrosis factor ligand superfamily member 7; CD70; CD27L; CD27LG; TNFSF7

Immunogen :Recombinant protein of human CD70.

Conjugate :Unconjugated

Modification :Unmodified

Western blot (WB) analysis of CD70 polyclonal antibody at 1:2000 dilution Lane1:EC9706 whole cell lysate(30ug) Lane2:MCF-7 whole cell lysate(30ug) Lane3:CT-26 whole cell lysate(30ug)