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CD59 polyclonal antibody（KU）

货号: NCP0217P

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :NCP0217P

Product Name :CD59 polyclonal antibody（KU）

Swiss-Prot :P13987

Host :Rabbit

Reactivity :Human

Applications :WB IF

Application_all :WB: 1:1000~1:2000 IF 1:50~1:200

Background :Potent inhibitor of the complement membrane attack complex (MAC) action. Acts by binding to the C8 and/or C9 complements of the assembling MAC, thereby preventing incorporation of the multiple copies of C9 required for complete formation of the osmolytic pore. This inhibitor appears to be species-specific. Involved in signal transduction for T-cell activation complexed to a protein tyrosine kinase.The soluble form from urine retains its specific complement binding activity, but exhibits greatly reduced ability to inhibit MAC assembly on cell membranes.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :CD59 polyclonal antibody detects endogenous levels of CD59 protein.

BiowMW :~17 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :CD59 glycoprotein; 1F5 antigen; 20 kDa homologous restriction factor; HRF-20; HRF20; MAC-inhibitory protein; MAC-IP; MEM43 antigen; Membrane attack complex inhibition factor; MACIF; Membrane inhibitor of reactive lysis; MIRL; Protectin; CD59

Immunogen :Recombinant protein of human CD59.

Conjugate :Unconjugated

Modification :Unmodified

Western blot (WB) analysis of CD59 polyclonal antibody at 1:1000 dilution Lane1:MCF-7 cell membrane lysate(25ug) Lane2:A549 cell membrane lysate(25ug) Lane3:L02 cell membrane lysate(25ug)

Immunofluorescence analysis of MCF-7 cells using CD59 pAb at dilution of 1:200.