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CD31 polyclonal antibody（KU）

货号: NCP0199P

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

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No. :NCP0199P

Product Name :CD31 polyclonal antibody（KU）

Swiss-Prot :P16284

Host :Rabbit

Reactivity :Human

Applications :WB IP IF

Application_all :WB: 1:5000~1:10000 IP 1:50 - 1:200 IF 1:100 - 1:500

Background :CD31 (Platelet Endothelial Cell Adhesion Molecule-1: PECAM-1), a member of the Ig superfamily of cell adhesion molecules, is expressed by circulating platelets, monocytes, neutrophils, some T cells, and endothelial cells and modulates cell adhesion, endothelial cell migration, and angiogenesis. CD31 is phosphorylated on Tyr686 at the cytoplasmic carboxy-terminal tail upon various stimuli (e.g. mechanical or oxidative stress), presumably by Src family members. The tyrosine phosphorylation mediates associations with a number of SH2 domain-containing binding partners such as PI3 kinase, SHIP, PLCγ, and SHP-2. Thus, CD31 serves as a scaffold for various signaling molecules.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :CD31 polyclonal antibody detects endogenous levels of CD31 protein.

BiowMW :~ 130 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Platelet endothelial cell adhesion molecule; PECAM-1; EndoCAM; GPIIA'; PECA1; CD31; PECAM1

Immunogen :Recombinant protein of human CD31.

Conjugate :Unconjugated

Modification :Unmodified

Western blot (WB) analysis of CD31 polyclonal antibody at 1:5000 dilution Lane1:Jurkat whole cell lysate(30ug) Lane2:THP-1 whole cell lysate(30ug) Lane3:A549 whole cell lysate(30ug)

Immunofluorescence analysis of MG63 cells using CD31 pAb at dilution of 1:200 (40x lens).