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CD171/N-CAML1 polyclonal antibody（KU）

货号: NCP0182P

价格：￥ 1140

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :NCP0182P

Product Name :CD171/N-CAML1 polyclonal antibody（KU）

Swiss-Prot :P32004

Host :Rabbit

Reactivity :Human

Applications :WB IP IF

Application_all :WB: 1:1000~1:2000 IP 1:50 - 1:200 IF 1:100 - 1:500

Background :Neural cell adhesion molecule L1 (NCAM-L1/L1CAM) is a single pass transmembrane glycoprotein member of the immunoglobulin superfamily, containing six amino-terminal extracellular Ig-like domains followed by five fibronectin type-III domains. NCAM-L1 is mainly expressed in the brain, and plays an important role in the developing nervous system, with involvement in neurite fasciculation and outgrowth, myelination, neuronal migration, and neuronal cell adhesion. Mutations in the NCAM-L1 gene cause varying degrees of neurological disease including X-linked hydrocephalus, MASA syndrome, spastic paraplegia type 1, and X-linked corpus callosum agenesis, together known as L1 syndrome. Apart from the nervous system, NCAM-L1 is overexpressed in many cancers and supports a poor prognosis by facilitating aggressive tumor growth, metastasis, and chemoresistance.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :CD171/N-CAML1 polyclonal antibody detects endogenous levels of CD171/N-CAML1 protein.

BiowMW :~ 200 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Neural cell adhesion molecule L1; N-CAM-L1; NCAM-L1; CD171; L1CAM; CAML1; MIC5

Immunogen :Recombinant protein of human CD171/N-CAML1.

Conjugate :Unconjugated

Modification :Unmodified

Western blot (WB) analysis of CD171/N-CAML1 polyclonal antibody at 1:1000 dilution Lane1:MCF-7 whole cell lysate(30ug) Lane2:SGC7901 cell membrane lysate(24ug)

Immunofluorescence analysis of MG63 cells using CD171/N-CAML1 pAb at dilution of 1:200 (40x lens).