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CD109 polyclonal antibody（KU）

货号: NCP0172P

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :NCP0172P

Product Name :CD109 polyclonal antibody（KU）

Swiss-Prot :Q6YHK3

Host :Rabbit

Reactivity :Human

Applications :WB IF

Application_all :WB: 1:1000~1:2000 IF 1:50~1:200

Background :CD109 is a glycosylphosphatidylinositol (GPI)-linked glycoprotein that belongs to the alpha2-macroglobulin family of thioester containing proteins. CD109 is associated with TGF-beta receptor I (TbRI) and inhibits TGF-beta signaling. Cleavage of CD109 at its Furin cleavage site results in the release of its large amino-terminal domain, which then binds to the TGF-beta receptor I to inhibit TGF-beta signaling. CD109 is expressed on a subset of CD34+ bone marrow cells and mesenchymal stem cells, activated platelets, activated T cells, endothelial cells, and a wide variety of tumors. Elevated CD109 expression has been considered a diagnostic/prognostic marker for several types of cancers.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :CD109 polyclonal antibody detects endogenous levels of CD109 protein.

BiowMW :~ 180 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :CD109 antigen; 150 kDa TGF-beta-1-binding protein; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 7; Platelet-specific Gov antigen; p180; r150; CD109; CPAMD7

Immunogen :Recombinant protein of human CD109.

Conjugate :Unconjugated

Modification :Unmodified

Western blot (WB) analysis of CD109 polyclonal antibody at 1:1000 dilution Lane1:A549 cell membrane lysate(24ug) Lane2:A375 whole cell lysate(24ug)

Immunofluorescence analysis of A549 cells using CD109 pAb at dilution of 1:200.