产品类别

联系我们

电话:025-68037686

地址:江苏生命科技创新园F6幢1层

订购:nanjing03@biogot.com

服务:biorase01@biogot.com

合作:lvyun@biogot.com

支持:may@biogot.com

COX4 (5B9) monoclonal antibody（KU）

货号: MB8007

价格：￥ 1350

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

抗体定制服务咨询

说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :MB8007

Product Name :COX4 (5B9) monoclonal antibody（KU）

Swiss-Prot :P13073

Host :Mouse

Reactivity :Human,Mouse,Rat

Applications :WB

Application_all :WB: 1:500~1:2000

Background :Cytochrome c oxidase (COX) is the terminal enzyme of the mitochondrial respiratory chain.It is a multi-subunit enzyme complex that couples the transfer of electrons from cytochrome c to molecular oxygen and contributes to a proton electrochemical gradient across the inner mitochondrial membrane.The complex consists of 13 mitochondrial- and nuclear-encoded subunits.The mitochondrially-encoded subunits perform the electron transfer and proton pumping activities.The functions of the nuclear-encoded subunits are unknown but they may play a role in the regulation and assembly of the complex.This gene encodes the nuclear-encoded subunit IV isoform 1 of the human mitochondrial respiratory chain enzyme.It is located at the 3´ of the NOC4 (neighbor of COX4) gene in a head-to-head orientation,and shares a promoter with it.

Product :1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :COX4 (5B9) monoclonal antibody detects endogenous levels of COX4 and does not cross-react with related proteins.

BiowMW :~ 20 kDa

Note :For research use only, not for use in diagnostic procedure.

Pathway :AMPK Signaling Pathway,

Alternative Name :Cytochrome c oxidase subunit 4 isoform 1, mitochondrial; Cytochrome c oxidase polypeptide IV; Cytochrome c oxidase subunit IV isoform 1; COX IV-1; COX4I1; COX4

Immunogen :Recombinant full length Human COX4.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of COX4 (5B9) mAb at 1:2000 dilution Lane1:SGC7901 whole cell lysate(20ug) Lane2:HCT116 whole cell lysate(20ug) Lane3:Panc1 whole cell lysate(20ug) Lane4:The Heart tissue lysate of Mouse(20ug) Lane5:The Heart tissue lysate of Rat(20ug) Lane6:H9C2 whole cell lysate(40ug)