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FOLH1 mouse monoclonal antibody

货号: MB67306

价格：￥ ——

货期：现货（1-2个工作日）

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No. :MB67306

Product Name :FOLH1 mouse monoclonal antibody

Swiss-Prot :Q04609

Host :Mouse

Reactivity :Human,Rat

Applications :WB, IF, ELISA

Application_all :WB 1:500~2000, IF 1:100

Background :This gene encodes a type II transmembrane glycoprotein belonging to the M28 peptidase family. The protein acts as a glutamate carboxypeptidase on different alternative substrates, including the nutrient folate and the neuropeptide N-acetyl-l-aspartyl-l-glutamate and is expressed in a number of tissues such as prostate, central and peripheral nervous system and kidney. A mutation in this gene may be associated with impaired intestinal absorption of dietary folates, resulting in low blood folate levels and consequent hyperhomocysteinemia. Expression of this protein in the brain may be involved in a number of pathological conditions associated with glutamate excitotoxicity. In the prostate the protein is up-regulated in cancerous cells and is used as an effective diagnostic and prognostic indicator of prostate cancer. This gene likely arose from a duplication event of a nearby chromosomal region. Alternative splicing gives rise to multiple transcript variants encoding several different isoforms.

Product :PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Purification&Purity :Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :FOLH1 mouse monoclonal antibody detects endogenous levels of FOLH1 protein.

BiowMW :~ 89 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :FGCP; FOLH; GCP2; GCPII; mGCP; NAALAD1; NAALAdase; PSM; PSMA

Immunogen :Full length human recombinant protein of human FOLH1(NP_004467) produced in HEK293T cell.

Conjugate :Unconjugated

Modification :Unmodified

Western blot (WB) analysis of FOLH1 mouse monoclonal antibody at 1:500 dilution Lane1:PC12 whole cell lysate(30ug) Lane2:PC3 whole cell lysate(30ug) Lane3:HCT116 whole cell lysate(30ug)