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DGKA mouse monoclonal antibody

货号: MB67304

价格：￥ ——

货期：现货（1-2个工作日）

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No. :MB67304

Product Name :DGKA mouse monoclonal antibody

Swiss-Prot :P19237

Host :Mouse

Reactivity :Human

Applications :WB,IHC

Application_all :WB 1:500, IHC 1:150

Background :Troponin proteins associate with tropomyosin and regulate the calcium sensitivity of the myofibril contractile apparatus of striated muscles. Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit; blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. The TnI-fast and TnI-slow genes are expressed in fast-twitch and slow-twitch skeletal muscle fibers, respectively, while the TnI-cardiac gene is expressed exclusively in cardiac muscle tissue. This gene encodes the Troponin-I-skeletal-slow-twitch protein. This gene is expressed in cardiac and skeletal muscle during early development but is restricted to slow-twitch skeletal muscle fibers in adults. The encoded protein prevents muscle contraction by inhibiting calcium-mediated conformational changes in actin-myosin complexes.

Product :PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Purification&Purity :Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :DGKA mouse monoclonal antibody detects endogenous levels of DGKA protein.

BiowMW :~ 80 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :SSTNI; TNN1

Immunogen :Full length human recombinant protein of human TNNI1 (NP_003272) produced in E.coli.

Conjugate :Unconjugated

Modification :Unmodified

Western blot (WB) analysis of DGKA mouse monoclonal antibody at 1:500 dilution Lane1:EC9706 whole cell lysate(30ug) Lane2:HCT116 whole cell lysate(30ug)