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VEGFR1 monoclonal antibody

货号: MB66912

价格：￥ 1350

货期：现货（1-2个工作日）

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No. :MB66912

Product Name :VEGFR1 monoclonal antibody

Swiss-Prot :P17948

Host :Mouse

Reactivity :Human

Applications :WB

Application_all :WB (1/500 - 1/1000)

Background :Galectin-3/LGALS3 is involved in several diverse biological functions. Galectin-3/LGALS3 binds IgE. Galectin-3/LGALS3 is an unusual protein in that it can be found both extracellularly and intracellularly. Intracellularly, Galectin-3/LGALS3 can localize to the cytoplasm, nucleus, or both, depending on cell type and experimental conditions. Nuclear Galectin-3/LGALS3 has been identified as a pre-mRNA splicing factor . Galectin-3/LGALS3 production has been shown to increase during inflammation and in obesity, and the protein itself can have an inflammatory effect under certain conditions . Galectin-3/LGALS3 forms a complex with 伪3, 尾1 integrin to act as a surface receptor on endothelial cells for the NG2 proteoglycan, which triggers cell motility and angiogenesis. In addition to these functions, Galectin-3/LGALS3 is also a required factor for the terminal differentiation of epithelial cells.

Product :Mouse IgG1 kappa. Liquid in PBS, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Purification&Purity :This antibody is purified through a protein G column.

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Recognizes endogenous levels of VEGFR1 protein.

BiowMW :~ 63 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :FLT; FRT; VEGFR1; Vascular endothelial growth factor receptor 1; VEGFR-1; Fms-like tyrosine kinase 1; FLT-1; Tyrosine-protein kinase FRT; Tyrosine-protein kinase receptor FLT; FLT; Vascular permeability factor receptor

Immunogen :Recombinant fusion protein of human VEGFR1. The exact sequence is proprietary.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of VEGFR1 expression in human lung (A) whole cell lysates.