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Glucocorticoid Receptor monoclonal antibody

货号: MB66792

价格：￥ 1350

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :MB66792

Product Name :Glucocorticoid Receptor monoclonal antibody

Swiss-Prot :P04150

Host :Mouse

Reactivity :Human, Mouse

Applications :WB

Application_all :WB (1/500 - 1/1000)

Background :The glucocorticoid receptor (GR) is a ubiquitously expressed transcription factor that mediates the effects of glucocorticoids. The most abundant isoform is GR a. GR induces or represses the expression of genes in response to glucocorticoids, mediating such processes as apoptosis, cell growth and differentiation. A significant class of genes suppressed by GR is controlled by the transcription factor AP-1. GR has also been shown to be the limiting factor in the induction of gene expression by glucocorticoids. It has been revealed that GR forms a complex with HSP 90, rendering the non-ligand bound receptor transcriptionally inactive. More importantly, mutant GRs lacking the signaling domain remain constitutively active.

Product :Mouse IgG1 kappa. Liquid in PBS, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Purification&Purity :This antibody is purified through a protein G column.

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Recognizes endogenous levels of Glucocorticoid Receptor protein.

BiowMW :~ 84 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :GRL; Glucocorticoid receptor; GR; Nuclear receptor subfamily 3 group C member 1

Immunogen :Recombinant fusion protein of human Glucocorticoid Receptor. The exact sequence is proprietary.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of Glucocorticoid Receptor expression in HeLa (A), A549 (B), CCRFCEM (C), CHO (D) whole cell lysates.

免疫沉淀（IP）