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MBP monoclonal antibody

货号: MB66778

价格：￥ 1350

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :MB66778

Product Name :MBP monoclonal antibody

Swiss-Prot :P02686

Host :Mouse

Reactivity :Human

Applications :WB, IF/ICC

Application_all :WB (1/1000 - 1/5000), IF/ICC (1/10 - 1/50)

Background :Myelin basic protein (MBP) is the major extrinsic membrane protein of central nervous system myelin. MBP phosphorylation at Threonine 125 is a complex regulatory process that modulates the contribution of MBP to the stability of the myelin sheath. Mitogen-activated protein kinases modulate MBP phosphorylation during myelinogenesis and in the demyelinating disease multiple sclerosis. MBP phosphorylation is regulated by high-frequency stimulation but not low-frequency stimulation of the alveus, the myelinated output fibers of the hippocampus. It is proposed that during periods of increased neuronal activity, calcium activates axonal nitric oxide synthase, which generates the intercellular messengers nitric oxide and superoxide and regulates the phosphorylation state of MBP by MAPK.

Product :Mouse IgM. Supplied in crude ascites with 0.01% sodium azide.

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Recognizes endogenous levels of MBP protein.

BiowMW :~ 31 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Myelin basic protein; MBP; Myelin A1 protein; Myelin membrane encephalitogenic protein

Immunogen :Recombinant fusion protein of human MBP. The exact sequence is proprietary.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of MBP expression in ZR751 (A) whole cell lysates.

免疫沉淀（IP）

免疫组织化学（IHC）