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Adenylate Kinase 1 monoclonal antibody

货号: MB66754

价格：￥ 1350

货期：现货（1-2个工作日）

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No. :MB66754

Product Name :Adenylate Kinase 1 monoclonal antibody

Swiss-Prot :P00568

Host :Mouse

Reactivity :Human

Applications :WB

Application_all :WB (1/1000 - 1/2000)

Background :Adenylate kinases 1-5 (designated AK1-5) are a set of enzymes that regulate the phosphorylation state of intracellular adenine nucleotides, which are the principle high-energy phosphoryl-carrying molecules in living cells.AKs influence metabolic signals, which include gene expression, ion channel activity and protein kinase-mediated signaling, by catalyzing phosphoryl transfer between adenine nucleotides (AMP, ADP, ATP). Inherited mutations leading to AK deficiencies in erythrocytes have been implicated in hemolytic anemia. Human AK1 is found in the cytosol of skeletal muscle, brain and erythrocytes and is clustered within myofibrils or bound to membranes. AK1-mediated phosphotransfer is essential for maintaining sufficient cellular energy,which enables proper skeletal muscle performance and metabolic activity.

Product :Mouse IgG1 kappa. Liquid in PBS, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Purification&Purity :This antibody is purified through a protein G column.

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Recognizes endogenous levels of Adenylate Kinase 1 protein.

BiowMW :~ 27 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Adenylate kinase isoenzyme 1; AK 1; ATP-AMP transphosphorylase 1; ATP:AMP phosphotransferase; Adenylate monophosphate kinase; Myokinase

Immunogen :Recombinant fusion protein of human Adenylate Kinase 1. The exact sequence is proprietary.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of Adenylate Kinase 1 expression in 293 (A), HepG2 (B), human testis (C) whole cell lysates.