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MAFK monoclonal antibody

货号: MB66733

价格：￥ 1350

货期：现货（1-2个工作日）

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No. :MB66733

Product Name :MAFK monoclonal antibody

Swiss-Prot :O60675

Host :Mouse

Reactivity :Human

Applications :WB, FC

Application_all :WB (1/500 - 1/1000), FC (1/10 - 1/50)

Background :Members of the Maf family of basic region/leucine zipper (bZIP) transcription factors affect transcription in either a positive or negative fashion, depending on their particular protein partner and the context of the target promoter.c-Maf (Maf-2) and the closely related family members Neural retina leucine zipper (Nrl), L-Maf and Krml1/MafB (Maf-1) all bind to T-MARE sites and are implicated in a wide variety of developmental and physiologic roles. The three small Maf family proteins MafF, MafG and MafK are components of NF-E2 which function as heterodimers with the large tissue restricted subunit of NF-E2 called p45, and furthermore are implicated in the transcriptional regulation of many erythroid-specific genes. MafG is ubiquitously expressed, with highest expression in the VMS, heart and skeletal muscle; its expression is induced in response to stress. MafK, also designated NF-E2 p18, is primarily expressed during development in mesenchymal and hematopoietic cells and neurons. MafK heterodimerizes with NF-E2 and various CNC proteins. MafF is most abundantly expressed in the lung and is thought to compensate for loss of function mutations in MafG and MafK.

Product :Mouse IgG1 kappa. Liquid in PBS, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Purification&Purity :This antibody is purified through a protein G column.

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Recognizes endogenous levels of MAFK protein.

BiowMW :~ 16 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Transcription factor MafK; Erythroid transcription factor NF-E2 p18 subunit

Immunogen :KLH-conjugated synthetic peptide of human MAFK. The exact sequence is proprietary.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of MAFK expression in Jurkat (A) whole cell lysates.

免疫沉淀（IP）