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GMFG monoclonal antibody

货号: MB66726

价格：￥ 1350

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :MB66726

Product Name :GMFG monoclonal antibody

Swiss-Prot :O60234

Host :Mouse

Reactivity :Human

Applications :WB

Application_all :WB (1/2000 - 1/10000)

Background :GMF-γ (glia maturation factor, γ), also known as GMFG, is a 142 amino acid protein that belongs to the GMF subfamily of the larger Actin-binding protein ADF family. GMF-γ is expressed predominantly in lung, heart and placenta.GMF-γ is considered a candidate regulatory growth factor protein, mediating both paracrine and autocrine cell-cell interactions. GMF-γ is phosphorylated at N-terminal serine, and its phosphorylation is enhanced by coexpression of dominant active Rac 1 and Cdc42. GMF-γ expression is significantly increased in a cardiac ischemia/reperfusion model where inflammation and angiogenesis take place actively. As a regulator of Actin-based cellular functions, GMF-γ may provide a novel approach to modulate the pathophysiology of cardiovascular diseases. GMF-γ is primarily found in proliferative and differentiative organs.

Product :Mouse IgG1. Supplied in crude ascites with 0.01% sodium azide.

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Recognizes endogenous levels of GMFG protein.

BiowMW :~ 14 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Glia maturation factor gamma; GMF-gamma

Immunogen :Recombinant fusion protein of human GMFG. The exact sequence is proprietary.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of GMFG expression in Jurkat (A) whole cell lysates.

免疫沉淀（IP）

免疫组织化学（IHC）