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VEGFD monoclonal antibody

货号: MB66725

价格：￥ 1350

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :MB66725

Product Name :VEGFD monoclonal antibody

Swiss-Prot :O43915

Host :Mouse

Reactivity :Human, Mouse

Applications :WB

Application_all :WB (1/500 - 1/1000)

Background :The onset of angiogenesis is believed to be an early event in tumorigenesis and may facilitate tumor progression and metastasis.Several growth factors with angiogenic activity have been described. These include fibroblast growth factor (FGF), platelet derived growth factor (PDGF) and vascular endothelial growth factor (VEGF). Several forms of VEGF have been identified, including VEGF, VEGF-B, VEGF-C and VEGF-D (also designated FIGF).Characteristic of VEGF proteins, the central region of VEGF-D contains eight cysteine residues.These residues are essential for homodimerization. VEGF-D may play a role in tumor progression, as it is induced by c-Fos, which is required for conversion of early stage tumors to malignant tumors. It has been observed that overexpression of VEGF-D induces morphological changes in fibroblasts.

Product :Mouse IgG1. Liquid in PBS, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Purification&Purity :This antibody is purified through a protein G column.

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Recognizes endogenous levels of VEGFD protein.

BiowMW :~ 40 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :VEGFD; Vascular endothelial growth factor D; VEGF-D; c-Fos-induced growth factor; FIGF

Immunogen :KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human VEGFD. The exact sequence is proprietary.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of VEGFD expression in MCF7 (A) whole cell lysates.

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