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FOXP2 monoclonal antibody

货号: MB66719

价格：￥ 1350

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :MB66719

Product Name :FOXP2 monoclonal antibody

Swiss-Prot :O15409

Host :Mouse

Reactivity :Human

Applications :WB

Application_all :WB (1/500 - 1/1000)

Background :Forkhead box (Fox) proteins are a family of evolutionarily conserved transcription factors containing a sequence known as Forkhead box or winged helix DNA binding domain. The human genome contains 43 Fox proteins that are divided into subfamilies. The FoxP subfamily has four members, FoxP1 - FoxP4, which are broadly expressed and play important roles in organ development, immune response and cancer pathogenesis. The FoxP subfamily has several characteristics that are atypical among Fox proteins: their Forkhead domain is located at the carboxy-terminal region and they contain motifs that promote homo- and heterodimerization. FoxP proteins usually function as transcriptional repressors. FoxP2 regulates lung and nerve system development. Mutations, including point mutation, truncation, deletion, and chromosomal translocation, involving FoxP2 are associated with an inherited form of speech and language disorder.

Product :Mouse IgM. Supplied in crude ascites with 0.01% sodium azide.

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Recognizes endogenous levels of FOXP2 protein.

BiowMW :~ 72 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :CAGH44; TNRC10; Forkhead box protein P2; CAG repeat protein 44; Trinucleotide repeat-containing gene 10 protein

Immunogen :KLH-conjugated synthetic peptide encompassing a sequence within the center region of human FOXP2. The exact sequence is proprietary.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of FOXP2 expression in 293 (A) whole cell lysates.

免疫沉淀（IP）

免疫组织化学（IHC）