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Hexokinase 1 monoclonal antibody

货号: MB66660

价格：￥ 1350

货期：现货（1-2个工作日）

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No. :MB66660

Product Name :Hexokinase 1 monoclonal antibody

Swiss-Prot :P19367

Host :Mouse

Reactivity :Human, Mouse, Rat

Applications :WB

Application_all :WB (1/500 - 1/1000)

Background :Hexokinase catalyzes the conversion of glucose to glucose-6-phosphate, the first step in glycolysis. Four distinct mammalian hexokinase isoforms, designated as hexokinase I, II, III, and IV (glucokinase), have been identified. Hexokinases I, II, and III are associated with the outer mitochondrial membrane and are critical for maintaining an elevated rate of aerobic glycolysis in cancer cells (Warburg Effect) in order to compensate for the increased energy demands associated with rapid cell growth and proliferation.

Product :Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Purification&Purity :The antibody was purified by immunogen affinity chromatography.

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Recognizes endogenous levels of Hexokinase 1 protein.

BiowMW :~ 102 kDa

Note :For research use only, not for use in diagnostic procedure.

Pathway :Warburg Effect

Alternative Name :Hexokinase-1; Brain form hexokinase; Hexokinase type I; HK I

Immunogen :Purified recombinant human Hexokinase 1 protein fragments expressed in E.coli

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of Hexokinase 1 expression in MCF7 (A), Jurkat (B), CHOK1 (C), C2C12 (D), C6 (E), NIH3T3 (F), Hela (G) whole cell lysates.