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TFIIB monoclonal antibody

货号: MB66646

价格：￥ 1350

货期：现货（1-2个工作日）

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No. :MB66646

Product Name :TFIIB monoclonal antibody

Swiss-Prot :Q00403

Host :Mouse

Reactivity :Human, Mouse, Monkey

Applications :WB

Application_all :WB (1/500 - 1/1000)

Background :TFIIB (also known as GTF2B, TF2B and general transcription factor IIB) is a ubiquitously expressed transcription factor that plays a central role in the assembly of the transcription pre-initiation complex through direct recruitment of RNA polymerase II. TFIIB functions as a bridge between promoter-bound TFIID and RNA polymerase II. In addition to interacting with promoter-bound TFIID and TFIIA, TFIIB makes extensive contacts with the core promoter via two independent DNA-binding modules. TFIIB may also be a target of transcriptional activator proteins that act to stimulate pre-initiation complex assembly.

Product :Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Purification&Purity :The antibody was purified by immunogen affinity chromatography.

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Recognizes endogenous levels of TFIIB protein.

BiowMW :~ 35 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :TF2B; TFIIB; Transcription initiation factor IIB; General transcription factor TFIIB; S300-II

Immunogen :Purified recombinant human TFIIB protein fragments expressed in E.coli.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of TFIIB expression in Jurkat (A), MCF7 (B), COS7 (C), NIH3T3 (D), Hela (E) whole cell lysates.

免疫沉淀（IP）