产品类别

联系我们

电话:025-68037686

地址:江苏生命科技创新园F6幢1层

订购:nanjing03@biogot.com

服务:biorase01@biogot.com

合作:lvyun@biogot.com

支持:may@biogot.com

RNF81 monoclonal antibody

货号: MB66618

价格：￥ 1350

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

抗体定制服务咨询

说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :MB66618

Product Name :RNF81 monoclonal antibody

Swiss-Prot :P19474

Host :Mouse

Reactivity :Human

Applications :WB

Application_all :WB (1/500 - 1/1000)

Background :Tripartite motif-containing protein 21 (TRIM21) is a cytosolic antiviral protein that is induced by interferons and acts as a cytosolic IgG receptor. TRIM21 is an activator of the innate immune system and targets antibody bound virions to the proteasome via its E3 ubiquitin ligase activity, leading to degradation of the virions in the cytosol. Interestingly, TRIM21 has also been shown to negatively regulate pathogen-induced interferon production through the polyubiquitin-mediated degradation of multiple targets including IRF3, IRF7, and DDX41.

Product :Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Purification&Purity :The antibody was purified by immunogen affinity chromatography.

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Recognizes endogenous levels of RNF81 protein.

BiowMW :~ 50 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :RNF81; RO52; SSA1; E3 ubiquitin-protein ligase TRIM21; 52 kDa Ro protein; 52 kDa ribonucleoprotein autoantigen Ro/SS-A; RING finger protein 81; Ro(SS-A); Sjoegren syndrome type A antigen; SS-A; Tripartite motif-containing protein 21

Immunogen :Purified recombinant human TRIM21 protein fragments expressed in E.coli.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of RNF81 expression in MCF7 (A), 293T (B), Hela (C) whole cell lysates.