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HSP60 monoclonal antibody

货号: MB66596

价格：￥ 1350

货期：现货（1-2个工作日）

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No. :MB66596

Product Name :HSP60 monoclonal antibody

Swiss-Prot :P10809

Host :Mouse

Reactivity :Human, Mouse, Rat

Applications :WB, IF/ICC, IP

Application_all :WB (1/500 - 1/1000), IF/ICC (1/50 - 1/100), IP (1/10 - 1/50)

Background :In both prokaryotic and eukaryotic cells the misfolding and aggregation of proteins during biogenesis and under conditions of cellular stress are prevented by molecular chaperones. HSP60 has primarily been known as a mitochondrial protein that is important for folding key proteins after import into the mitochondria. Research studies have shown that a significant amount of HSP60 is also present in the cytosol of many cells, and that it is induced by stress, inflammatory and immune responses, and autoantibodies correlated with Alzheimer's, coronary artery diseases, MS, and diabetes.

Product :Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Purification&Purity :The antibody was purified by immunogen affinity chromatography.

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Recognizes endogenous levels of HSP60 protein.

BiowMW :~ 60 kDa

Note :For research use only, not for use in diagnostic procedure.

Pathway :Mitochondrial Control of Apoptosis

Alternative Name :HSP60; 60 kDa heat shock protein mitochondrial; 60 kDa chaperonin; Chaperonin 60; CPN60; Heat shock protein 60; HSP-60; Hsp60; HuCHA60; Mitochondrial matrix protein P1; P60 lymphocyte protein

Immunogen :Purified recombinant human Hsp60 protein fragments expressed in E.coli.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of HSP60 expression in Hela (A), Raji (B), Jurkat (C), C6 (D), C2C12 (E), NIH3T3 (F) whole cell lysates.