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BAX monoclonal antibody

货号: MB66572

价格：￥ 1350

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :MB66572

Product Name :BAX monoclonal antibody

Swiss-Prot :Q07812

Host :Mouse

Reactivity :Human, Monkey

Applications :WB

Application_all :WB (1/500 - 1/1000)

Background :Bax is a key component for cellular induced apoptosis through mitochondrial stress. Upon apoptotic stimulation, Bax forms oligomers and translocates from the cytosol to the mitochondrial membrane. Through interactions with pore proteins on the mitochondrial membrane, Bax increases the membrane's permeability, which leads to the release of cytochrome c from mitochondria, activation of caspase-9, and initiation of the caspase activation pathway for apoptosis.

Product :Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Purification&Purity :The antibody was purified by immunogen affinity chromatography.

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Recognizes endogenous levels of BAX protein.

BiowMW :~ 20 kDa

Note :For research use only, not for use in diagnostic procedure.

Pathway :Regulation of Apoptosis，Mitochondrial Control of Apoptosis，Inhibition of Apoptosis，PI3K AKT signaling，SAPK JNK Signaling Cascades，Warburg Effect

Alternative Name :BCL2L4; Apoptosis regulator BAX; Bcl-2-like protein 4; Bcl2-L-4

Immunogen :Purified recombinant human Bax protein fragments expressed in E.coli

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of BAX expression in COS7 (A), Raji (B), CEM (C), Hela (D) whole cell lysates.