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CDX2 monoclonal antibody

货号: MB66550

价格：￥ 1350

货期：现货（1-2个工作日）

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No. :MB66550

Product Name :CDX2 monoclonal antibody

Swiss-Prot :Q99626

Host :Mouse

Reactivity :Human, Mouse, Monkey

Applications :WB, IF/ICC, IP

Application_all :WB (1/500 - 1/1000), IF/ICC (1/50 - 1/100), IP (1/10 - 1/50)

Background :CDX2, a homeobox domain-containing transcription factor, is a master regulator of the trophectoderm, the layer that gives rise to extra-embryonic tissues in mammalian development. CDX2 is also involved in intestinal development, and gain of expression or loss of expression has been associated with various human malignancies, such as Barrett's esophagus and colorectal cancer. Mouse embryonic stem cells deficient in CDX2 display limited hematopoietic progenitor development and altered Hox gene expression, pointing to a role for CDX2 in Hox gene regulation. CDX2 is also implicated in the aberrant expression of Hox genes in human AML cell lines.

Product :Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Purification&Purity :The antibody was purified by immunogen affinity chromatography.

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Recognizes endogenous levels of CDX2 protein.

BiowMW :~ 38 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :CDX3; Homeobox protein CDX-2; CDX-3; Caudal-type homeobox protein 2

Immunogen :Purified recombinant human CDX2 protein fragments expressed in E.coli

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of CDX2 expression in Hela (A), Caco2 (B), C2C12 (C), SW480 (D), COS7 (E), HepG2 (F), NIH3T3 (G) whole cell lysates.

免疫沉淀（IP）