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CALU monoclonal antibody

货号: MB66536

价格：￥ 1350

货期：现货（1-2个工作日）

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No. :MB66536

Product Name :CALU monoclonal antibody

Swiss-Prot :O43852

Host :Mouse

Reactivity :Human, Mouse

Applications :WB

Application_all :WB (1/500 - 1/1000)

Background :Calumenin belongs to the CREC family of proteins that also contains reticulocalbin, ERC-55/TCBP-49/E6BP, Cab45, and crocalbin/CBP-50. These EF-hand proteins localize to the endoplasmic reticulum (ER) and are involved in the secretory pathway in mammalian cells. Calumenin exists as two isoforms corresponding to alternativly spliced variants of the CALU gene. Calumenin has been shown to localize to the ER via a carboxy terminal HDEF ER retention signal, and undergoes secretion after trafficking through the secretory pathway. Secreted calumenin plays a role in amyloidosis by interacting with serum amyloid P component. Calumenin is also a chaperone for mutants of the cystic fibrosis transmembrane conductance regulator (CFTR). Researchers performing a proteomics analysis of endometrial cancer identified calumenin as a potential target for endometrial carcinoma.

Product :Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Purification&Purity :The antibody was purified by immunogen affinity chromatography.

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Recognizes endogenous levels of CALU protein.

BiowMW :~ 47 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Calumenin; Crocalbin; IEF SSP 9302

Immunogen :Purified recombinant human Calumenin protein fragments expressed in E.coli.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of CALU expression in SW480 (A), mouse intestine (B), A431 (C) whole cell lysates.

免疫沉淀（IP）