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Syntenin monoclonal antibody

货号: MB66524

价格：￥ 1350

货期：现货（1-2个工作日）

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No. :MB66524

Product Name :Syntenin monoclonal antibody

Swiss-Prot :O00560

Host :Mouse

Reactivity :Human

Applications :WB

Application_all :WB (1/500 - 1/1000)

Background :Syntenin-1 (MDA9, SDCBP) is a member of the PDZ family of proteins, defined by the presence of a PDZ protein interaction domain. Syntenin-1, via its PDZ domain, functions as a scaffold adaptor protein that regulates numerous signal transduction pathways, including FAK, Src, TGFβR1, EGFR, and IGF1R. Aberrantly elevated expression of syntenin-1 has been found in various cancers, and has been linked to growth and invasion of tumor cells. In the central nervous system, syntenin-1 has been shown to mediate neuron dendrite protrusion and spine formation through its interaction with syndecan and Rheb. Syntenin-1 is also a key component of the syndecan/syntenin/ALIX pathway which has been shown to directly contribute to the formation and internalization of exosomes.

Product :Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Purification&Purity :The antibody was purified by immunogen affinity chromatography.

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Recognizes endogenous levels of Syntenin protein.

BiowMW :~ 30 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :MDA9; SYCL; Syntenin-1; Melanoma differentiation-associated protein 9; MDA-9; Pro-TGF-alpha cytoplasmic domain-interacting protein 18; TACIP18; Scaffold protein Pbp1; Syndecan-binding protein 1

Immunogen :Purified recombinant human Syntenin protein fragments expressed in E.coli.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of Syntenin expression in Hela (A), Hela (B) whole cell lysates.