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SAF-B1 monoclonal antibody

货号: MB66523

价格：￥ 1350

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

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No. :MB66523

Product Name :SAF-B1 monoclonal antibody

Swiss-Prot :Q15424

Host :Mouse

Reactivity :Human

Applications :WB, IF/ICC, ChIP

Application_all :WB (1/500 - 1/1000), IF/ICC (1/50 - 1/100), ChIP (1/10 - 1/50)

Background :Binds to scaffold/matrix attachment region (S/MAR) DNA and forms a molecular assembly point to allow the formation of a 'transcriptosomal' complex (consisting of SR proteins and RNA polymerase II) coupling transcription and RNA processing.Functions as an estrogen receptor corepressor and can also bind to the HSP27 promoter and decrease its transcription.Thereby acts as a negative regulator of cell proliferation,When associated with RBMX, binds to and stimulates transcription from the SREBF1 promoter (By similarity).

Product :Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Purification&Purity :The antibody was purified by immunogen affinity chromatography.

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Recognizes endogenous levels of SAF-B1 protein.

BiowMW :~ 130 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :HAP; HET; SAFB1; Scaffold attachment factor B1; SAF-B; SAF-B1; HSP27 estrogen response element-TATA box-binding protein; HSP27 ERE-TATA-binding protein

Immunogen :Purified recombinant human SAFB1 protein fragments expressed in E.coli.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of SAF-B1 expression in Hela (A), A431 (B), MDAMB468 (C), ZR751 (D), MCF7 (E) whole cell lysates.