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SMYD1 monoclonal antibody

货号: MB66489

价格：￥ 1350

货期：现货（1-2个工作日）

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No. :MB66489

Product Name :SMYD1 monoclonal antibody

Swiss-Prot :D4A3D2

Host :Mouse

Reactivity :Rat

Applications :WB

Application_all :WB (1/500 - 1/1000)

Background :SMYD1 (SET and MYND domain-containing protein 1), also known as BOP, ZMYND18 or ZMYND22, is a nuclear and cytoplasmic protein that contains one SET domain and one MYND-type zinc finger. Expressed specifically in cardiac and skeletal muscle, SMYD1 functions as a transcription factor that is essential for cardiac morphogenesis and proper cardiomyocyte differentiation. SMYD1 interacts with the histone deacetylases HDAC1, HDAC2 and HDAC3 and, through this interaction, acts as a histone deacetylase-dependent transcriptional repressor. Defects or deletions in the gene encoding SMYD1 lead to retarded maturation of ventricular cardiomyocytes, further implicating SMYD1 as a crucial component of normal cardiac development.

Product :Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Purification&Purity :The antibody was purified by immunogen affinity chromatography.

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Recognizes endogenous levels of SMYD1 protein.

BiowMW :~ 57 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Histone-lysine N-methyltransferase SMYD1; SET and MYND domain-containing protein 1

Immunogen :Purified recombinant human SMYD1 protein fragments expressed in E.coli.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of SMYD1 expression in rat skeletal muscle (A) whole cell lysates.

免疫沉淀（IP）