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ATF3 Rabbit monoclonal antibody

货号: MB66422

价格：￥ 1350

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

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说明书 MSDS SHIP

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No. :MB66422

Product Name :ATF3 Rabbit monoclonal antibody

Swiss-Prot :P18847

Host :Rabbit

Reactivity :Human

Applications :WB, IP

Application_all :WB (1/500 - 1/1000), IP (1/10 - 1/50)

Background :Activating transcription factor 3 (ATF-3) is a basic leucine zipper-type transcription factor belonging to the ATF/cAMP responsive element binding protein family. ATF-3 can form homodimers or heterodimers with other family members and depending on the cell types and promoter context, it can suppress or activate the transcription of its target genes. Expression of ATF-3 is induced by a variety of factors including cytokines, genotoxic agents, and physiological stress. For example, both metformin and high-density lipoprotein (HDL) can induce ATF-3 expression in macrophages. Research studies also indicate that ATF-3 can function as an oncogene or a tumor suppressor depending on the context .

Product :Liquid in 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 50% Glycerol, 0.01% Sodium azide and 0.05% BSA.

Purification&Purity :The antibody was purified by immunogen affinity chromatography.

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Recognizes endogenous levels of ATF3 protein.

BiowMW :~ 23 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Cyclic AMP-dependent transcription factor ATF-3; cAMP-dependent transcription factor ATF-3; Activating transcription factor 3

Immunogen :Recombinant protein of human ATF3

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of ATF3 expression in MCF7 (A), U251 (B), HL60 (C) whole cell lysates.

免疫沉淀（IP）