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Presenilin 1 Rabbit monoclonal antibody

货号: MB66379

价格：￥ 1350

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

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No. :MB66379

Product Name :Presenilin 1 Rabbit monoclonal antibody

Swiss-Prot :P49768

Host :Rabbit

Reactivity :Human, Mouse, Rat

Applications :WB, IF/ICC, IP

Application_all :WB (1/500 - 1/1000), IF/ICC (1/50 - 1/100), IP (1/10 - 1/50)

Background :Presenilin 1 and presenilin 2 are transmembrane proteins belonging to the presenilin family. Mutation of presenilin genes has been linked to early onset of Alzheimer disease, probably due to presenilin's associated γ-secretase activity for amyloid-β protein processing . Endogenous presenilin mainly exists in a heterodimeric complex formed from the endoproteolytically processed amino-terminal (34 kDa) and carboxy-terminal (~20, 22, 23 kDa) fragments (CTF) .

Product :Liquid in 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 50% Glycerol, 0.01% Sodium azide and 0.05% BSA.

Purification&Purity :The antibody was purified by immunogen affinity chromatography.

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Recognizes endogenous levels of Presenilin 1 protein.

BiowMW :~ 22 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :AD3; PS1; PSNL1; Presenilin-1; PS-1; Protein S182

Immunogen :A synthetic peptide of human Presenilin 1

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of Presenilin 1 expression in Hela (A), C6 (B), Jurkat (C), mouse colon (D), mouse gastric (E) whole cell lysates.

免疫沉淀（IP）