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JNK1 Rabbit monoclonal antibody

货号: MB66362

价格：￥ 1350

货期：现货（1-2个工作日）

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No. :MB66362

Product Name :JNK1 Rabbit monoclonal antibody

Swiss-Prot :Q91Y86/P49185

Host :Rabbit

Reactivity :Mouse, Rat

Applications :WB, IF/ICC, IP

Application_all :WB (1/500 - 1/1000), IF/ICC (1/50 - 1/100), IP (1/10 - 1/50)

Background :Serine/threonine-protein kinase involved in various processes such as cell proliferation, differentiation, migration, transformation and programmed cell death. Extracellular stimuli such as pro-inflammatory cytokines or physical stress stimulate the stress-activated protein kinase/c-Jun N-terminal kinase (SAP/JNK) signaling pathway. In this cascade, two dual specificity kinases MAP2K4/MKK4 and MAP2K7/MKK7 phosphorylate and activate MAPK8/JNK1. In turn, MAPK8/JNK1 phosphorylates a number of transcription factors, primarily components of AP-1 such as JUN, JDP2 and ATF2 and thus regulates AP-1 transcriptional activity.

Product :Liquid in 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 50% Glycerol, 0.01% Sodium azide and 0.05% BSA.

Purification&Purity :The antibody was purified by immunogen affinity chromatography.

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Recognizes endogenous levels of JNK1 protein.

BiowMW :~ 46, 54 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :JNK1; PRKM8; SAPK1; SAPK1C; Mitogen-activated protein kinase 8; MAP kinase 8; MAPK 8; JNK-46; Stress-activated protein kinase 1c; SAPK1c; Stress-activated protein kinase JNK1; c-Jun N-terminal kinase 1

Immunogen :Recombinant protein of human JNK1

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of JNK1 expression in C6 (A), NIH3T3 (B) whole cell lysates.