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JAK2 Rabbit monoclonal antibody

货号: MB66361

价格：￥ 1350

货期：现货（1-2个工作日）

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No. :MB66361

Product Name :JAK2 Rabbit monoclonal antibody

Swiss-Prot :O60674

Host :Rabbit

Reactivity :Human, Mouse

Applications :WB

Application_all :WB (1/500 - 1/1000)

Background :Members of the Janus family of tyrosine kinases (Jak1, Jak2, Jak3, and Tyk2) are activated by ligands binding to a number of associated cytokine receptors. Upon cytokine receptor activation, Jak proteins become autophosphorylated and phosphorylate their associated receptors to provide multiple binding sites for signaling proteins. These associated signaling proteins, such as Stats, Shc , insulin receptor substrates, and focal adhesion kinase (FAK), typically contain SH2 or other phospho-tyrosine-binding domains.

Product :Liquid in 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 50% Glycerol, 0.01% Sodium azide and 0.05% BSA.

Purification&Purity :The antibody was purified by immunogen affinity chromatography.

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Recognizes endogenous levels of JAK2 protein.

BiowMW :~ 125 kDa

Note :For research use only, not for use in diagnostic procedure.

Pathway :ErbB HER Signaling，Jak Stat ：IL-6 Receptor Signaling，Inhibition of Apoptosis

Alternative Name :Tyrosine-protein kinase JAK2; Janus kinase 2; JAK-2

Immunogen :A synthetic peptide of human JAK2

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of JAK2 expression in K562 (A), NIH3T3 (B) whole cell lysates.