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GFAP Rabbit monoclonal antibody

货号: MB66274

价格：￥ 1350

货期：现货（1-2个工作日）

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No. :MB66274

Product Name :GFAP Rabbit monoclonal antibody

Swiss-Prot :P14136

Host :Rabbit

Reactivity :Human, Rat

Applications :WB, IHC, IF/ICC

Application_all :WB (1/500 - 1/1000), IHC (1/50 - 1/100), IF/ICC (1/50 - 1/100)

Background :The cytoskeleton consists of three types of cytosolic fibers: microfilaments (actin filaments), intermediate filaments, and microtubules. Major types of intermediate filaments are specifically expressed in particular cell types: cytokeratins in epithelial cells, glial fibrillary acidic protein (GFAP) in glial cells, desmin in skeletal, visceral, and certain vascular smooth muscle cells, vimentin in cells of mesenchymal origin, and neurofilaments in neurons. GFAP and vimentin form intermediate filaments in astroglial cells and modulate their motility and shape. In particular, vimentin filaments are present at early developmental stages, while GFAP filaments are characteristic of differentiated and mature brain astrocytes. Thus, GFAP is commonly used as a marker for intracranial and intraspinal tumors arising from astrocytes. In addition, GFAP intermediate filaments are also present in nonmyelin-forming Schwann cells in the peripheral nervous system.

Product :Liquid in 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 50% Glycerol, 0.01% Sodium azide and 0.05% BSA.

Purification&Purity :The antibody was purified by immunogen affinity chromatography.

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Recognizes endogenous levels of GFAP protein.

BiowMW :~ 54 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Glial fibrillary acidic protein; GFAP

Immunogen :A synthetic peptide of human GFAP

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of GFAP expression in rat brain (A), Hela (B) whole cell lysates.

免疫沉淀（IP）