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PGD Rabbit monoclonal antibody

货号: MB66264

价格：￥ 1350

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

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No. :MB66264

Product Name :PGD Rabbit monoclonal antibody

Swiss-Prot :P52209

Host :Rabbit

Reactivity :Human, Mouse, Rat

Applications :WB, IF/ICC, IP

Application_all :WB (1/500 - 1/1000), IF/ICC (1/50 - 1/100), IP (1/10 - 1/50)

Background :6-phosphogluconate dehydrogenase (PGD or 6PGD) catalyzes the conversion of 6-phosphogluconate and NADP+ to ribulose 5-phosphate and NADPH in the pentose phosphate pathway. Research studies show that knockdown of PGD results in the induction of senescence and inhibition of growth of lung cancer cells. Additional research suggests that PGD influences the migration of some cancer cells by regulating c-Met phosphorylation state. Furthermore, it was shown that the glycolytic enzyme PGAM1 substrate (3-phosphoglycerate) regulates the pentose phosphate pathway by deactivating PGD/6PGD.

Product :Liquid in 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 50% Glycerol, 0.01% Sodium azide and 0.05% BSA.

Purification&Purity :The antibody was purified by immunogen affinity chromatography.

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Recognizes endogenous levels of PGD protein.

BiowMW :~ 52 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :PGDH; 6-phosphogluconate dehydrogenase decarboxylating

Immunogen :A synthetic peptide of human PGD

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of PGD expression in C6 (A), NIH3T3 (B), Hela (C) whole cell lysates.

免疫沉淀（IP）