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Doublecortin Rabbit monoclonal antibody

货号: MB66252

价格：￥ 1350

货期：现货（1-2个工作日）

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No. :MB66252

Product Name :Doublecortin Rabbit monoclonal antibody

Swiss-Prot :Q9ESI7

Host :Rabbit

Reactivity :Rat

Applications :WB

Application_all :WB (1/500 - 1/1000)

Background :Microtubule-associated protein required for initial steps of neuronal dispersion and cortex lamination during cerebral cortex development. May act by competing with the putative neuronal protein kinase DCLK1 in binding to a target protein. May in that way participate in a signaling pathway that is crucial for neuronal interaction before and during migration, possibly as part of a calcium ion-dependent signal transduction pathway. May participate along with PAFAH1B1/LIS-1 in a distinct overlapping signaling pathway that promotes neuronal migration.

Product :Liquid in 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 50% Glycerol, 0.01% Sodium azide and 0.05% BSA.

Purification&Purity :The antibody was purified by immunogen affinity chromatography.

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Recognizes endogenous levels of Doublecortin protein.

BiowMW :~ 41 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :DBCN; LISX; Neuronal migration protein doublecortin; Doublin; Lissencephalin-X; Lis-X

Immunogen :Recombinant protein of human Doublecortin

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of Doublecortin expression in rat brain (A) whole cell lysates.

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