Product Name :MSH2 monoclonal antibody
Application_all :WB (1/500 - 1/1000), IHC (1/100 - 1/300)
Background :The DNA mismatch repair system (MMR) repairs post-replication DNA, inhibits recombination between non-identical DNA sequences and induces both checkpoint and apoptotic responses following certain types of DNA damage . MSH2 (MutS homologue 2) forms the hMutS-α dimer with MSH6 and is an essential component of the mismatch repair process. hMutS-α is part of the BRCA1-associated surveillance complex (BASC), a complex that also contains BRCA1, MLH1, ATM, BLM, PMS2 proteins and the Rad50-Mre11-NBS1 complex
Product :Mouse IgG. Liquid in PBS containing 50% glycerol, 0.2% BSA and 0.01% sodium azide.
Purification&Purity :The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :Recognizes endogenous levels of MSH2 protein.
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :DNA mismatch repair protein Msh2; hMSH2; MutS protein homolog 2
Immunogen :KLH-conjugated synthetic peptide encompassing a sequence within human MSH2. The exact sequence is proprietary.
Modification :Unmodification
